If you are looking for the FAQ specific to Pain Management and Opioids, please go here.

What is NEJM Knowledge+?

NEJM Knowledge+ is family of comprehensive learning and assessment products for clinicians to efficiently maintain and grow their clinical knowledge on an ongoing basis, earn required CME, and approach their certification exams with confidence. Learn more here.

Why should I use NEJM Knowledge+ over other products?

NEJM Knowledge+ combines gold-standard content with the most efficient, engaging, and effective way to help you learn, improve the quality of your practice, and prepare for board exams.

NEJM Knowledge+MKSAPMedStudyMedChallengerAAFP Self-StudyBoard VitalsTrueLearn
More than 1,600 case-based questionsXXX
Multiple question formats (long, short, and fill-in-the-blank)XX
Adaptive learning experience with personalized review
recommendations
XX
Earn MOC pointsXXX
Earn CME creditsXXXXXX
Mobile access availableXXXXXXX
From a highly trusted, not-for-profit providerXXX
Metacognitive reporting of self-awarenessXXX
Timed practice exams that simulate the board experienceXXXXXXX
Live customer support 24x7x365X

What products are available?

Our current products are Internal Medicine Board Review, Family Medicine Board Review, and Pediatrics Board Review. We also offer Pain Management and Opioids as a CME module within Internal Medicine Board Review and Family Medicine Board Review. We may launch additional products for other specialists and health care professionals in the future.

What is included in NEJM Knowledge+?

Purchasing a full product gives you access to

  • A robust question bank of case-based questions that are
    • Guided by your board’s blueprint (ABIM, AAFP, ABP, or NCCPA)
    • Served adaptively to create a personalized learning experience
    • Delivered in multiple formats to optimize learning and retention
    • Rigorously reviewed and edited by your peers
  • Two (2) practice exams that approximate the experience of taking the board exams
  • The ability to earn CME credits and MOC points
  • Detailed reports on progress and performance, the learning objectives and questions that you’ve found most challenging, as well as how your confidence matches your performance
  • The ability to search questions you have seen already
  • Convenient, mobile access
  • Customer support is available 24 hours a day, 7 days a week, 365 days a year
  • Free access to New England Journal of Medicine articles, and links to other citations.

Purchasing a Focus Module(s) gives you access to

  • A subspecialty specific question bank of case-based questions that are
    • Guided by your board’s blueprint (ABIM, AAFP, ABP, or NCCPA)
    • Served adaptively to create a personalized learning experience
    • Delivered in multiple formats to optimize learning and retention
    • Rigorously reviewed and edited by your peers
  • The ability to earn CME credits and MOC points
  • Detailed reports on progress and performance, the learning objectives and questions that you’ve found most challenging, as well as how your confidence matches your performance
  • Convenient, mobile access
  • Customer support is available 24 hours a day, 7 days a week, 365 days a year
  • Free access to cited New England Journal of Medicine articles and links to other citations.

Registering to free Pain Management and Opioids course gives you access to:

  • A subspecialty specific question bank of sixty-two case-based questions in eight (8) topic areas with feedback that are
    • Mapped to the FDA Opioid REMS blueprint
    • Served adaptively to create a personalized learning experience
    • Delivered in multiple formats to optimize learning and retention
    • Rigorously reviewed and edited by your peers
  • Linked to clinical tools and downloadable learning resources relevant to daily practice
  • The ability to earn CME credits and MOC points
  • Detailed reports on progress and performance, the learning objectives and questions that you’ve found most challenging, as well as how your confidence matches your performance
  • Convenient, mobile access
  • Customer support is available 24 hours a day, 7 days a week, 365 days a year
  • Free access to cited New England Journal of Medicine articles and links to other citations.

Is NEJM Knowledge+ appropriate as a USMLE study tool?

NEJM Knowledge+ is not relevant for Step 1. USMLE focuses on basic science and mechanistic questions whereas NEJM Knowledge+ is primarily clinical. It is more relevant for Step 2 and very relevant for Step 3.

What is the cost?

The cost for NEJM Knowledge+ Internal Medicine Board Review is $650 for physicians and $399 for residents, fellows, and other health care professionals. See pricing for more details.

The cost for NEJM Knowledge+ Family Medicine Board Review is $650 for physicians and $399 for residents, students, fellows, physician assistants, nurse practitioners, and other health care professionals. See pricing for more details.

The cost for NEJM Knowledge+ Pediatrics Board Review is $650 for physicians and $399 for residents, fellows, and other health care professionals. See pricing for more details.

Pain Management and Opioids activity is offered free of charge thanks to support by an independent educational grant from the Opioid Analgesic REMS Program Companies.

Can I get a group discount?

We are happy to discuss special pricing for group practices and other group sales. Please complete the form on our Group Sales page and someone will contact you with detailed information.

How long will I have access to my NEJM Knowledge+ product?

Your purchase term is one full year of access to the product. You can purchase one-year extensions up until a new version of the product is launched. The current price for a one-year extension is $150. You will have access to your MOC/CME transcripts for up to six years after your term expires.

The Pain Management and Opioids module is offered at no cost for a term of three (3) years from the date of registration.

How do I purchase NEJM Knowledge+ products?

You can purchase NEJM Knowledge+ products by using the Buy Now button on any page of the NEJM Knowledge+ website (see above) or go directly to the order form to purchase.

How do I access the product(s) I’ve already purchased?

To access your personalized NEJM Knowledge+ product, please follow the Log in Now link on your profile page. You can bookmark the destination link or continue to access the product through your profile.

How do I sign in/log in?

Please use the Sign In button at the top right of any page on this website or sign in/log in here.

I can’t remember the email address on my account.

Contact our Customer Support Team and we will be happy to help you retrieve your account information.

I have forgotten my password – how can I retrieve it?

Go to the Forgot Password page, enter the email address associated with your account, and click “Continue.” You will receive an email with a link to reset your password. Please note that the link will expire within 45 minutes. If you’re not able to reset your password within that time frame we suggest that you wait until you will be able to perform the reset. Your password should be 6 to 20 characters long.

Why can’t I sign in/log in with my NEJM.org credentials?

NEJM Knowledge+, the New England Journal of Medicine, NEJM Journal Watch, NEJM Catalyst, and NEJM Resident 360 are all products of NEJM Group but are separate products and require separate registration/purchase and separate credentials to access the product. Please use the Buy Now button at the top of this page if you would like to purchase and NEJM Knowledge+ product or register for the Pain Management and Opioids module.

What kinds of help and support will be available to me?

You may contact Customer Support 24 hours a day, 7 days a week, 365 days a year with any questions. We can help you with questions about purchasing, accessing, or using the product.

How can I contact Customer Support?

You can reach Customer Support at any time:

For technical issues, it will help us serve you faster if you are able to provide the device, browser, and operating system you are using, and any error messages you encounter.

If you need assistance with your subscription to the New England Journal of Medicine or NEJM Journal Watch, or if you have questions about CME related to Interactive Medical Cases, please contact nejmcust@mms.org.

Can other people use my NEJM Knowledge+ product?

We strongly recommend that you do not share your NEJM Knowledge+ account information with anyone. NEJM Knowledge+ uses an adaptive learning engine that provides each user with a personalized learning experience and performance data. If you share your account with other people, you will not get the full benefit of the product. Additionally, the CME credits (and, where offered, MOC points) you earn are associated with your account only and cannot be transferred to others.

Are my data secure?

As an individual purchaser, your progress and performance data are yours alone. We have a 100% threshold for performance to earn CME credits and MOC points, and we give you multiple tries to get each question correct. All that your CME transcript or submission to the ABIM or ABP indicates are the questions you’ve answered correctly.

How can I earn CME credits with NEJM Knowledge+?

All of our questions have been approved for AMA PRA Category 1 Credit™. You will receive one (1) credit for every six (6) questions you answer correctly. You earn 1/6 of a credit the first time you answer a question correctly regardless of the format. With adaptive learning, you may see questions more than once and in more than one format so you may answer more questions correctly than are reported on your Dashboard.

How do I print my transcript?

The credits that you earn by answering questions in NEJM Knowledge+ products can be printed for submission as needed. Open the NEJM Knowledge+ product where your CME credits have accumulated.

  1. On the Dashboard, navigate to the credits center.
  2. Next, navigate to CME Transcripts.
  3. Use the date picker at the top of the page to set the date range for your transcript.
  4. Select the Print CME Transcript button and then print the following page using your browser’s print functionality (for example, by pressing CTRL+P)

Why can’t I see the CME credits I am earning in Pain Management and Opioids yet?

Pain Management and Opioids enables you to earn up to 10 AMA PRA Category 1 Credits™ as well as additional continuing education credits and maintenance of certification points. Accreditation information is available at the bottom of this page as well as on the product description page of this site. All of our questions have been approved for AMA PRA Category 1 Credit™. You will receive one (1) credit for every six (6) questions you answer correctly. You earn 1/6 of a credit the first time you answer a question correctly regardless of the format.

It is important to note that CME credits that you earn while answering questions in Pain Management and Opioids will NOT display on the Dashboard, in the MOC/CME/Accreditation Center, or on a transcript until you have completed all of the initial case-based questions in the module.

If you cannot see how many CME credits you have earned, you should continue answering questions in the Pain Management and Opioids module. Once you have answered all 62 case-based questions you will be shown a congratulations message. At that time, you can go to the MOC/CME Center or Accreditation Center through the link on the Dashboard. From there, you can claim the CME credits you earned by answering questions correctly and, if you want to, you can continue to answer questions in the module to earn credits for any questions you answered incorrectly.

How can I earn ABIM MOC points with NEJM Knowledge+?

ABIM MOC points are available with NEJM Knowledge+ Internal Medicine Board Review. You automatically earn one (1) MOC point for every six (6) questions you answer correctly up to the number of MOC points for which the activity is approved. You earn 1/6 of a point the first time you answer a question correctly regardless of the format. With adaptive learning, you may see questions more than once and in more than one format so you may answer more questions correctly than are reported on your Dashboard.

Please be sure to update your profile with your ABIM number and date of birth, which will enable us to transmit the MOC points you have earned to the ACCME, which automatically sends this data to the ABIM each night. You will see these updates listed as NEJM Knowledge+ Internal Medicine Board Review on your ABIM profile the following day. You can also provide this ABIM number and date of birth later, by editing your profile.

How can I earn AAFP Prescribed credits with NEJM Knowledge+?

AAFP Prescribed credits are available with NEJM Knowledge+ Family Medicine Board Review. You can earn up to the number of AAFP Prescribed credits for which the activity is approved through our general and elective modules. You can easily keep track of your credits through the Accreditation Center available from within the application.

How can I earn ABMS MOC Part 2 Credits with NEJM Knowledge+?

American Board of Medical Specialties Maintenance of Certification Part 2 Credits are now available with NEJM Knowledge+ Pain Management and Opioids through the American Board of Medical Specialties (“ABMS”) ongoing commitment to increase access to practice relevant Continuing Certification Activities through the ABMS Continuing Certification Directory, NEJM Knowledge+ Pain Management and Opioids has met the requirements as an MOC Part II Self-Assessment and/or MOC Part II CME Activity (apply toward general CME requirement) for the following ABMS Member Boards:

MOC Part II Self-Assessment Activity

  • Physical Medicine and Rehabilitation

MOC Part II CME Activity

  • Anesthesiology
  • Family Medicine
  • Preventive Medicine
  • Psychiatry and Neurology
  • Radiology

How can I earn AAPA Self-Assessment credits with NEJM Knowledge+?

AAPA Self-Assessment credits are available with NEJM Knowledge+ Family Medicine Board Review. You can earn up to 20.00 AAPA Category 1 Self-Assessment CME credits through our general and elective modules. You can easily keep track of your credits through the Accreditation Center available from within the application.

AAPA Self-Assessment credits are available with NEJM Knowledge+ Pain Management and Opioids. You can earn up to 10.00 AAPA Category 1 Self-Assessment CME credits. You can easily keep track of your credits through the Accreditation Center available from within the application.

For NCCPA certification maintenance ONLY, NCCPA will now apply an additional 50 percent weighting when these self-assessment credits are logged for NCCPA certification maintenance purposes. PAs should log up to a maximum of 10.00 AAPA Category 1 Self-Assessment CME credits, as the additional weighting will be automatically applied by NCCPA.

How can I earn AANP Pharmacology Contact Hours with NEJM Knowledge+?

AANP credits are available for nurse practitioners with NEJM Knowledge+ Pain Management and Opioids. You can now earn 10.0 contact hour(s) of continuing education (which includes 10.0 hours of pharmacology) by the American Association of Nurse Practitioners. Activity ID 20034193. This activity was planned in accordance with AANP Accreditation Standards and Policies

How can I earn ACPE credit with NEJM Knowledge+?

ACPE credits are now available for pharmacists with NEJM Knowledge+ Pain Management and Opioids. You can earn 8.0 contact hours of continuing education. The ACPE universal activity number is: 0027-9999-19-069-H01-P.

How can I earn ABP MOC points with NEJM Knowledge+?

ABP MOC points are available with NEJM Knowledge+ Pediatrics Board Review. You automatically earn one (1) MOC point for every six (6) questions you answer correctly up up to the number of MOC points for which the activity is approved. You earn 1/6 of a point the first time you answer a question correctly regardless of the format. With adaptive learning, you may see questions more than once and in more than one format so you may answer more questions correctly than are reported on your Dashboard.

Please be sure to update your profile with your ABP number and date of birth, which will enable us to transmit the MOC points in batches of 10 points earned to the ABP on your behalf. You can also add your ABP information and see the number of points/credits earned when logged into Pediatrics Board Review, by going to the MOC/CME Center. You will receive 1 CME credit and 1 MOC point for every 6 correctly-answered questions and your points will be transmitted to the ABP in accordance with their requirements.

How do I claim my Continuing Pharmacy Credits?

Continuing Pharmacy Credits are available for prescribers who use the Pain Management and Opioids module. You can how to claim and submit your CPE credits at on our CPE page.

A score of 80% (8 CME credits) is required to claim CPE credit. If you have not yet earned 8 CME credits, you can continue to answer questions in the Pain Management and Opioids module. You receive one (1) credit for every six (6) questions you answer correctly. You earn 1/6 of a credit the first time you answer a question correctly regardless of the format.

Does NEJM Knowledge+ offer an app for iPad or iPhone?

NEJM Knowledge+ will no longer offer apps for our products as of late September 2022. The new NEJM Knowledge+ will work on any device anytime you have an internet connection and offers the full functionality of the desktop site.

Does NEJM Knowledge+ offer an app for Android devices?

NEJM Knowledge+ will no longer offer apps for our products as of late September 2022. The new NEJM Knowledge+ will work on any device anytime you have an internet connection and offers the full functionality of the desktop site.

What are the hardware and software requirements?

To access NEJM Knowledge+ Internal Medicine Board Review, NEJM Knowledge+ Family Medicine Board Review, and/or NEJM Knowledge+ Pediatrics Board Review on your desktop, sign in here if you purchased your own subscription and sign in here if your subscription is provided to you by your institution.

Adobe Reader is required.

Browsers 

In general, we support the two latest versions of major browsers: 

  • Edge (Recommended for best performance) 
  • Chrome (Recommended for best performance) 
  • Firefox 
  • Safari 

 Systems Minimum Requirements 

  • Screen Size: 4.5″+ (mobile) 
  • Some content types might not work on small screens 
  • Win10+ with 4GB+ RAM (8GB+ recommended) 
  • macOS 11+ with 4GB+ RAM (6GB+ recommended 
  • Android 10+ with 2GB+ RAM  
  • iOS 12+ with 2GB+ RAM (Devices from 2019+ recommended) 
  • Internet bandwidth: 1Mbit/s+ bandwidth (10MBit/s recommended, depends on content type)

NEJM Knowledge+ Full Product Accreditation

Accreditation Statement

The Massachusetts Medical Society is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.

The American Medical Association has an agreement of mutual recognition of Continuing Medical Education (CME) credits with the European Union of Medical Specialists (UEMS), the accreditation body for European countries. Physicians interested in converting AMA PRA Category 1 Credit™ to UEMS-European Accreditation Council for Continuing Medical Education CME credits (ECMECs) should contact the UEMS at mutualrecognition@uems.eu.

AMA Credit Designation Statement

The Massachusetts Medical Society designates each enduring material for the number of AMA PRA Category 1 Credits™ listed below. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

NEJM Knowledge Internal Medicine Board Review:  357 AMA PRA Category 1 Credits™

NEJM Knowledge+ Family Medicine Board Review: 349 AMA PRA Category 1 Credits™

NEJM Knowledge+ Pediatrics Board Review: 153 AMA PRA Category 1 Credits™

ABIM MOC Points

ABIM CME MOCSuccessful completion of this CME activity, which includes participation in the evaluation component, enables the participant to earn up to 357 MOC points in the American Board of Internal Medicine's (ABIM) Maintenance of Certification (MOC) program. Participants will earn MOC points equivalent to the amount of CME credits claimed for the activity. It is the CME activity provider's responsibility to submit participant completion information to ACCME for the purpose of granting ABIM MOC credit.

ABP MOC StatementABP MOC points

Successful completion of this CME activity, which includes participation in the activity and individual assessment of and feedback to the learner, enables the learner to earn up to 153 MOC points in the American Board of Pediatrics’ (ABP) Maintenance of Certification (MOC) program. It is the CME activity provider’s responsibility to submit learner completion information to ACCME for the purpose of granting ABP MOC credit.

AAFP Prescribed Credit

The AAFP has reviewed NEJM Knowledge+ Family Medicine Board Review and deemed it acceptable for up to 348.00 Enduring Materials, Self-Study AAFP Prescribed credits. Term of Approval is from 02/01/2023 to 12/31/2023. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Royal College of Physicians and Surgeons of Canada

Through an agreement between the Accreditation Council for Continuing Medical Education and the Royal College of Physicians and Surgeons of Canada, medical practitioners participating in the Royal College MOC Program may record completion of accredited activities registered under the ACCME’s “CME in Support of MOC” program in Section 3 of the Royal College’s MOC Program.

AAPA Category 1 Self-Assessment CMEAAPA CME Credit (NEJM Knowledge+ Family Medicine Board Review)

This activity has been reviewed by the AAPA Review Panel and is compliant with AAPA CME Criteria. This activity is designated for 20 AAPA Category 1 Self-Assessment CME credits. PAs should only claim credit commensurate with the extent of their participation. Approval is valid from 5/1/2023 to 4/30/2024. AAPA reference number: CME-209251.

For NCCPA certification maintenance ONLY: NCCPA will now apply an additional 50 percent weighting when these self-assessment credits are logged for NCCPA certification maintenance purposes. PAs should log up to a maximum of 20 AAPA Category 1 Self-Assessment CME credits, as the additional weighting will be automatically applied by NCCPA.

ACPE CreditsACPE Logo

The University of Rhode Island College of Pharmacy is accredited by the Accreditation Council for Pharmacy Education as a provider of continuing pharmacy education. This is an application-based educational activity. Pharmacists will receive 8.0 contact hours (0.8 CEUS) for the educational activity. No partial credit is available. UNIVERSAL ACTIVITY NUMBERS (UAN) 0060-9999-22-055-H08-P

NEJM Knowledge+ Pain Management and Opioids Accreditation

Accreditation Information
Disclosure of support

This activity is supported by an independent educational grant from the Opioid Analgesic REMS Program Companies. Please see https://www.opioidanalgesicrems.com/Resources/Docs/List_of_RPC_Companies.pdf for a listing of REMS Program Companies. This activity is intended to be fully compliant with the Opioid Analgesic REMS education requirements issued by the US Food and Drug Administration.

Accreditation Statement

The Massachusetts Medical Society is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.

AMA Credit Designation Statement

The Massachusetts Medical Society designates this enduring material for a maximum of 10 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Risk Management and Pain Management Credits

This activity meets the criteria of the Massachusetts Board of Registration in Medicine for risk management study.

This activity meets the criteria of the Massachusetts Board of Registration in Medicine for opioid education.

Many states have similar requirements. Please check with your Board to determine if this activity will fulfill your state's specific requirements.

American Board of Internal Medicine MOC Points

ABIM CME MOCNEJM Knowledge+ Pain Management and Opioids (IM) only:  Successful completion of this CME activity, which includes participation in the evaluation component, enables the participant to earn up to 10 MOC points and patient safety MOC credit in the American Board of Internal Medicine’s (ABIM) Maintenance of Certification (MOC) program. Participants will earn MOC points equivalent to the amount of CME credits claimed for the activity. It is the CME activity provider’s responsibility to submit participant completion information to ACCME for the purpose of granting ABIM MOC credit.

American Academy of Family Physicians (AAFP)

AAPA Category 1 Self-Assessment CMENEJM Knowledge+ Pain Management and Opioids (FM) only:  The AAFP has reviewed NEJM Knowledge+ Pain Management and Opioids and deemed it acceptable for up to 10.00 Enduring Materials, Self-Study AAFP Prescribed credits. Term of Approval is from 04/15/2023 to 04/15/2024. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

American Board of Medical Specialties Maintenance of Certification Part 2 Credit

Through the American Board of Medical Specialties (“ABMS”) ongoing commitment to increase access to practice relevant Continuing Certification Activities through the ABMS Continuing Certification Directory, NEJM Knowledge+ Pain Management and Opioids has met the requirements as an MOC Part II Self-Assessment and/or MOC Part II CME Activity (apply toward general CME requirement) for the following ABMS Member Boards:

MOC Part II Self-Assessment Activity Physical Medicine and Rehabilitation

MOC Part II CME Activity Anesthesiology, Family Medicine, Preventive Medicine, Psychiatry and Neurology, and Radiology

American Academy of Physician Assistants (AAPA)

This activity has been reviewed by the AAPA Review Panel and is compliant with AAPA CME Criteria. This activity is designated for 10 AAPA Category 1 CME credits. PAs should only claim credit commensurate with the extent of their participation. Approval is valid from 4/15/2023 to 4/14/2024. AAPA reference number: CME-209127.

American Association of Nurse Practitioners (AANP)

Pharmacology Contact Hours

This activity is approved for 10.0 contact hour(s) of continuing education (which includes 10.0 hours of pharmacology) by the American Association of Nurse Practitioners. Activity ID 23036011. This activity was planned in accordance with AANP Accreditation Standards and Policies.

ACPE Credits

ACPE LogoThe University of Rhode Island College of Pharmacy is accredited by the Accreditation Council for Pharmacy Education as a provider of continuing pharmacy education. This is an application-based educational activity. Pharmacists will receive 8.0 contact hours (0.8 CEUS) for the educational activity. No partial credit is available. UNIVERSAL ACTIVITY NUMBERS (UAN) 0060-9999-22-055-H08-P

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